For the young (and not so young) scientists, a very interesting interview from earlier on this year with the 2002 Physiology / Medicine Nobel Winner on innovation and scientific publishing.

Some very interesting thought about the need to tackle something you know nothing of in order not to bring your own biais:

The thing is to have no discipline at all. Biology got its main success by the importation of physicists that came into the field not knowing any biology and I think today that’s very important.

I strongly believe that the only way to encourage innovation is to give it to the young. The young have a great advantage in that they are ignorant.  Because I think ignorance in science is very important. If you’re like me and you know too much you can’t try new things. I always work in fields of which I’m totally ignorant…

And on the business of publications and the impact factor scam:

I think peer review is hindering science. In fact, I think it has become a completely corrupt system. It’s corrupt in many ways, in that scientists and academics have handed over to the editors of these journals the ability to make judgment on science and scientists. There are universities in America, and I’ve heard from many committees, that we won’t consider people’s publications in low impact factor journals.

Now I mean, people are trying to do something, but I think it’s not publish or perish, it’s publish in the okay places [or perish]. And this has assembled a most ridiculous group of people…

A very interesting read: How Academia and Publishing are Destroying Scientific Innovation: A Conversation with Sydney Brenner | King’s Review – Magazine.